Aspergillus Fumigatus Onychomycosis Treatment. When possible immunosuppressive therapy such as systemic corticosteroids should be discontinued. Onychomycosis of a toenail in a young woman was proved to be caused by Aspergillus fumigatus. Is non-specific but commonly distal-lateral pattern of onychomycosis. The clinical presentation of onychomycosis due to Aspergillus spp.
When possible immunosuppressive therapy such as systemic corticosteroids should be discontinued. Onychomycosis located in his toenails was found during the 6th week of treatment Figure 1. Antifungal cream or ointment applied to the affected nail is effective in some milder cases. Treatment consists of systemic therapy with terbinafine or itraconazole. Two weeks later the number of fungal elements that could be seen on direct examination was much reduced. Additionaly nail antifungal lacquers with ciclopirox or amorolfine as well as partial nail avulsion with 40 urea ointment usually improve the clinical response of systemic treatment.
Voriconazole is currently used as first-line treatment for invasive aspergillosis.
Sabouraud medium culture was obtained from the nail and aspergillus fumigatus multiplied in the medium after 1 week Figure 2. Prolonged treatment is usually required. The clinical presentation of onychomycosis due to Aspergillus spp. Antifungal cream or ointment applied to the affected nail is effective in some milder cases. Expert guidance is needed for infections not responding to treatment including antifungal-resistant infections. When possible immunosuppressive medications should be discontinued or decreasedPeople with severe cases of aspergillosis may need surgery.