14
Sep
Introduction Of Oral Drug Delivery System. The oral mucosa is an appropriate route for drug delivery systems as it evades first-pass metabolism enhances drug bioavailability and provides the means for rapid drug transport to the systematic circulation. KeywordsFilm forming polymers Lycoat Monoammonium glycyrrhizinate Oral thin. Films have all the advantages of tablets precise dosage easy administration and those of liquid dosage forms easy swallowing rapid bioavailability. Controlled Release Oral Drug Delivery System Controlled drug delivery is one which delivers the drug at a predetermined rate for locally or systemically for a.
KeywordsFilm forming polymers Lycoat Monoammonium glycyrrhizinate Oral thin. However disadvantages such as hepatic first pass metabolism and enzymatic degradation within the GI tract limits its use for certain drugs. Novel carrier systems S P Vyas and R K Khar CBS publishers 2002. 6 AuthorsHarsha Kathpalia and Aasavari Gupte AffiliationVivekanand Education Societys College of Pharmacy Hashu Advani Memorial Complex behind Collector Colony Chembur E Mumbai-400 074 India. O Progress in Controlled and Novel drug delivery systems by N K Jain CBS publishers 2008. Introduction Amongst the various routes of drug delivery oral route is the most preferred to the patient.
Transdermal drug delivery is defined as self contained discrete dosage forms which when applied to the intact skin deliver the drug through the skin at controlled rate to the systemic circulation.
The term oral drug delivery also referred to as peroral delivery refers to taking a dosage form by mouth for local action or systemic absorption at any point along the gastrointestinal GI tract. Gastro retentive drug delivery GRDDS is one of the site specific drug delivery for the delivery of the drugs at stomach. However disadvantages such as hepatic first pass metabolism and enzymatic degradation within the GI tract limits its use for certain drugs. Transdermal drug delivery is defined as self contained discrete dosage forms which when applied to the intact skin deliver the drug through the skin at controlled rate to the systemic circulation. Drug delivery systems DDSs are pharmaceutical formulations or devices that help in achieving targeted delivery andor controlled release CR of therapeutic agents in our body. Following administration the DDSs liberate the active ingredients and subsequently the bioactive molecules are transported across various biological barriers to reach the site of action.