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Mechanism Of Action Of Disinfectant. Sodium hypochlorite fulfills many requirements as the ideal disinfectant and furthermore it has an excellent cleaning action. Action on the bacterial wall. Mechanism of Action. Action on the external membrane of the bacterial wall.
2 Early studies on the action of such compounds concentrated on the kinetics of bacterial inactivation 3 although Cooper 4 notably described the relationship between phenolics phenol and meta-cresol and bacterial proteins as being of importance in their mechanism. How- ever the mode of action of chlorine and its com- pounds on microbial life is not yet fully understood. Is available on the physical chemistry of chlorine in aqueous solutions as well asthe kinetics of its bac- tericidal action Fair et al 1948. And targeted donation of biocide from delivery systems requiring an. Quaternary ammonium compounds QACs were described in 1916 but were not used commercially for another 19 years or so. Increasingly demanding disinfectant applications require more sophisticated use of biocidal systems.
Mechanisms of action of disinfectants.
And targeted donation of biocide from delivery systems requiring an. The exact mechanism of action of a disinfectant is not easy to elucidate. Intracellular biocide delivery using cellular transport processes to overcome cellular barriers. Is available on the physical chemistry of chlorine in aqueous solutions as well asthe kinetics of its bac- tericidal action Fair et al 1948. Mechanisms of antibacterial action The classical approach to determining a mechanism of action relies upon establishing a correlation between concentrations initiating bacteriostatic or bactericidal effects and those precipitating specific biochemical or physiological changes Bloomfield 1991. Disinfectants used for sanitation and cleaning in pharmaceutical industries must be selected on the basis of their mechanism of action.