28
Feb
Octanol Water Partition Coefficients Of Simple Organic Compounds. For more hydrophobic substances several experimental procedures have been proposed in the literature. Generator column determination of octanolwater partition coefficients for selected polychlorinated biphenyl congeners. More exactly in the partition equilibrium the octanol phase is a saturated solution of water in octanol and the aqueous. There Is No Job Too Small So Get In Touch With Our Experienced Team.
Pertinent thermodynamic relations are presented with a discussion of direct and. A short summary of this. Kcc OW O equil W equil 1 where c O equil concentration of the compound under consideration analyte A in 1-octanol in the equilibrium and c W equil concentration of the analyte in water in the equilibrium. Available experimental details of measurement are documented from original articles. Risk of molecular migration in foodpackaging system is important consideration from safety hygienic and economic points of view. The octanol-water partition coefficient is a laboratory-measured property of a substance.
It provides a thermodynamic measure of the tendency of the substance to prefer a non-aqueous or oily milieu rather than water ie.
Howarth Gary Kean Emilie Levet Daniel Wang Estelle Wayemberg Agnes A. Partition coefficients P Ow i describing the distribution of a solute i onto coexisting phases of 1-octanol and water are needed in a large variety of applications. A short summary of this. There Is No Job Too Small So Get In Touch With Our Experienced Team. 22 rows We describe a simple miniature shake-flask method to measure the octanolwater partition. For a non-ionizable compound the partition coefficient P is defined as the ratio of the concentration of the compound in two immiscible liquid phases such as octanol and waterFor practical purposes the logarithm of the partition coefficient log P is most commonly usedOctanol is the preferred partitioning solvent for most studies since with its hydrophobic tail and polar head group.