28
Sep
Platelet Function Collagen Adp. As control group 18 insulin-dependent diabetics were only monitored without attempts to normalize their blood glucose behaviour. Examples include the glycoprotein IIb-IIIa receptor which is targeted by antiplatelets such as tirafiban. Sensitive to quantitative and qualitative abnormalities of VWD in both plasma and platelets. Coagulation panels platelet counts and vWfAg are all normal.
Collagen fibrils within the vessel wall become exposed to the circulation when the endothelial cell monolayer is breached forming a complex with von Willebrand factor VWF. PLATELET FUNCTION REAGENTS Collagen Type 1. The importance of ADP in normal hemostasis is clearly demonstrated in patients suffering from storage pool disease who show excessive bleeding tendencies. The collagenepinephrine CEPI membrane detects platelet dysfunction induced by any intrinsic platelet defects von Willebrand disease aspirin etc. Adenine di-Phosphate ADP is an important physiological agonist that plays a vital role in normal hemostasis and thrombosis. In addition to collagen the membranes are coated epinephrine COLEPI or adenosine diphosphate COLADP which stimulates platelet aggregation.
If both tests are abnormal the patient may have a platelet function disorder and further testing for inherited or acquired bleeding disorders is indicated.
Collagenepinephrine COLEPI and collagenadenosine COLADP. Sensitive to quantitative and qualitative abnormalities of VWD in both plasma and platelets. There are two test cartridges currently available. Coagulation panels platelet counts and vWfAg are all normal. Collagen fibrils within the vessel wall become exposed to the circulation when the endothelial cell monolayer is breached forming a complex with von Willebrand factor VWF. The cartridge membrane is coated with collagen and with one of two platelet agonists epinephrine or ADP.