Pomegranate juice warfarin interaction

Pomegranate Juice Warfarin Interaction. Investigators from previous animal and in vitro studies have reported a potential for pomegranate juice to inhibit metabolism involving the cytochrome P450 system an effect that could translate into a clinical drugdiet interaction with warfarin. Investigators from previous animal and in vitro studies have reported a potential for pomegranate juice to inhibit metabolism involving the cytochrome P450 system an effect that could translate into a clinical drug-diet interaction with warfarin. Low glycemicblood pressure effects. Possible Interaction Between Pomegranate Juice and Warfarin.

We report a potential interaction between pomegranate juice and warfarin. Prune juice and warfarin taken together have not been shown to have any harmful effects. Some of these prescription medications may include Coumadin Vasotec. The whole fruit. Investigators from previous animal and in vitro studies have reported a potential for pomegranate juice to inhibit metabolism involving the cytochrome P450 system an effect that could translate into a clinical drugdiet interaction with warfarin. Low glycemicblood pressure effects.

We report a potential interaction between pomegranate juice and warfarin.

Twenty-three case reports and controlled clinical trials were evaluated and the majority involved cranberry products also the most frequently studied fruit. The whole fruit. Laboratory studies have shown that pomegranate juice inhibits cytochrome P450 enzymes involved in warfarin metabolism. Pomegranate juice may interact with certain medications especially those that help with high blood pressure or blood thinning. We report a potential interaction between pomegranate juice and warfarin. As with previous reports of interactions between food and warfarin this case does not definitively prove the association between pomegranate juice consumption and increased warfarin.