15
Apr
Selection Of Industrially Important Microorganisms. Effect of the preservation method on the viability of micro-organism. The screening of microorganisms for the production of useful products continues to be an important aspect of biotechnology. Mutation and recombinant dna techniques for. Discovering new microbial compounds and improving the synthesis of known ones.
Although advances in instrumentation genetics and microbial physiology are having an impact screening programs are still primarily based on so-called classical techniques of enrichment and mutagenesis. The use of methanol as an energy source. There are different methods for microbial preservation. The bio- synthesis of some antibiotics is known to be the highest in strains utilizing in- tensively fatty acids. An explanation of this phenomenon for mycelial organisms may be that most new isolates are probably heterokaryons contain more than one type of nucleus and the selection of the progeny of uninucleate spores results in the production of homokaryons contain only one type of nucleus which may be superior producers. A determination should be made about the yield potentialities of various isolated microorganisms that are detected in primary screening for that new compound.
Amylase protease Recombinant DNA technology has also been applied in medicine insulin HGH.
The bio- synthesis of some antibiotics is known to be the highest in strains utilizing in- tensively fatty acids. There are different methods for microbial preservation. The good sources for the isolation of microorganisms are soils lakes and river muds. 1 screening for desired properties among assemblages of known organisms or 2 the isolation or detection of novel organisms in the expectation that they will present novel behaviour. These requirements may be met by the suitable design of the isolation medium. The next step after isolation of microorganisms is the selection or screening.