Tacrolimus Ointment Vitiligo Results. First time posting here. Also known as. Successful treatment of vitiligo with tacrolimus has been reported See Table 1. 61 of those users who reviewed Tacrolimus topical reported a positive effect while 26 reported a negative effect.
To lower the risk of organ rejection Tacrolimus is given. Hands feet and lower legs were unresponsive. Besides the frequency of tacrolimus application the treatment outcome was determined by the localization of the affected areas with the facial region showing the best response. A guarded prognosis is advisable for vitiliginous lesions on other localizations. Patients with the greatest treatment response likely benefited from concomitant natural sunlight exposure. Tacrolimus sold under the brand names Protopic and Prograf among others is an immunosuppressive drugAfter allogeneic organ transplant the risk of organ rejection is moderate.
Oral tacrolimus has limited use in skin disorders because of its potentially severe adverse effects including infections hypertension hyperglycemia hyperkalemia nephrotoxic and neurotoxic effects and increased risk of neoplasia.
A guarded prognosis is advisable for vitiliginous lesions on other localizations. Topical tacrolimus ointment is an effective alternative therapy for childhood vitiligo particularly involving the head and neck. Tanghetti EA 2003 Tacrolimus ointment 01 produces repigmentation in patients with vitiligo. Results of a prospective patient series. It is made from a rare soil bacterium found only in Japan. Xu et al1 studied 30 vitiligo patients who were treated with tacrolimus ointment for 4 months or more.