What Causes Cleft Palate In Humans. The majority of cleft patients have no identifiable cause. MSX1 gene develop a cleft of the secondary palate and tooth agenesis. Probably only in about 2-8 of cases. On average about 1 in every 500-750 live births result in a cleft.
In the last few years there has been growing evidence that cleft lip and palate could be the result of poor vitamin B and folic acid levels in the mother. Cleft lip and cleft palate can also be corrected through effective treatment. Pierre Robin Sequence also knows as Pierre Robin Syndrome is caused by. Probably only in about 2-8 of cases. MSX1 gene develop a cleft of the secondary palate and tooth agenesis. Furthermore in the US the prevalence for cleft lip with or without cleft palate is 22 to 117 per 10000 births.
The mothers health is a contributing factor but scientists are still searching for other.
Causes of Cleft Palate and Lip The cause of cleft palate and lip isnt known but doctors believe that the defects occur because of both genetic and environmental factors. The exact reason why this happens to some babies is often unclear. Most cleft palates seem to be caused by environmental factors that increase a mothers risk of giving birth to a child with a cleft palate. Doctors think that cleft palates and cleft lips are rarely genetic. Doctors think that cleft palates and cleft lips are rarely genetic. In humans MSX1 mutation was first shown to cause an autosomal dominant form of tooth agenesis.